cagrilintide tirzepatide combination study Efficacy and safety of once-weekly cagrilintide–semaglutide (CagriSema) in adults with type 2 diabetes inadequately controlled on diet and exercise (REIMAGINE 1): a randomised, double-blind, placebo-controlled, phase 3a Size:1000 mcg/ml - 30 ml x 1 5-amino-1mq – New England B Injection

cagrilintide tirzepatide combination study Efficacy and safety of once-weekly cagrilintide–semaglutide (CagriSema) in adults with type 2 diabetes inadequately controlled on diet and exercise (REIMAGINE 1): a randomised, double-blind, placebo-controlled, phase 3a Size:1000 mcg/ml - 30 ml x 1 5-amino-1mq – New England B Injection

5-amino-1mq – New England Peptide Center

Direct increases in collagen mRNA production occur across the effective concentration range of 0.01 to 100 nanomolar

B Injection

Size:1000 mcg/ml - 30 ml x 1

Optimal Storage Conditions Lyophilized powder: -20°C to -80°C in freezer Reconstituted solution: 2°C to 8°C in refrigerator Protected from direct light exposure Sealed containers to prevent contamination Upright positioning in storage Storage Duration Guidelines Unopened powder: 12-24 months frozen Reconstituted with bacteriostatic water: 4-6 weeks refrigerated Reconstituted with sterile water: 72 hours refrigerated After first puncture: Follow bacteriostatic water guidelines Discard if discoloration or particles appear Monitoring Solution Integrity Inspect reconstituted solutions before each use